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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOPEY2 All Species: 16.36
Human Site: S1177 Identified Species: 27.69
UniProt: Q9Y3R5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3R5 NP_005119.2 2298 258184 S1177 F K A G A K L S L V R V D S D
Chimpanzee Pan troglodytes XP_531552 2298 258112 S1177 F K A G A K L S L V R V D S D
Rhesus Macaque Macaca mulatta XP_001084653 2286 256620 S1165 F K A G A K L S L V R V D S D
Dog Lupus familis XP_544874 2297 257913 G1177 F R P S A R L G L A R V D S D
Cat Felis silvestris
Mouse Mus musculus Q3UHQ6 2295 257491 S1175 P R S N A R L S L V R A D S D
Rat Rattus norvegicus XP_001055500 2294 257490 S1174 P R S N A R L S L V R A D S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512569 2247 251024 R1169 A S E P R R R R K E E Q E A T
Chicken Gallus gallus XP_001232723 2283 257889 R1167 L V R A D S E R T Q A S E S L
Frog Xenopus laevis Q642P2 2270 256829 D1158 T L V R T E S D V T Q T S E S
Zebra Danio Brachydanio rerio NP_956904 817 86774
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZBE8 2599 291169 E1425 N I S G S H V E Q P E Q E E E
Honey Bee Apis mellifera XP_395999 2434 273219 P1293 F E A S V E V P S W T M D D E
Nematode Worm Caenorhab. elegans Q9XW10 2417 267134 L1245 N R M L L N C L V S S G T T T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03921 1698 194669 L638 K I P E S E E L K G R S H I S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.8 89.9 N.A. 86.4 86.4 N.A. 73.9 75.2 69 21.9 N.A. 27.6 32.1 22.3 N.A.
Protein Similarity: 100 99.7 96 94.6 N.A. 92.4 92.5 N.A. 83 85.4 82 28.7 N.A. 47 53.2 40.9 N.A.
P-Site Identity: 100 100 100 60 N.A. 60 60 N.A. 0 6.6 0 0 N.A. 6.6 20 0 N.A.
P-Site Similarity: 100 100 100 73.3 N.A. 80 80 N.A. 20 13.3 20 0 N.A. 40 53.3 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 29 8 43 0 0 0 0 8 8 15 0 8 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 8 0 0 0 0 50 8 43 % D
% Glu: 0 8 8 8 0 22 15 8 0 8 15 0 22 15 15 % E
% Phe: 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 29 0 0 0 8 0 8 0 8 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 15 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 8 22 0 0 0 22 0 0 15 0 0 0 0 0 0 % K
% Leu: 8 8 0 8 8 0 43 15 43 0 0 0 0 0 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 15 0 0 15 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 15 0 15 8 0 0 0 8 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 8 8 15 0 0 0 % Q
% Arg: 0 29 8 8 8 29 8 15 0 0 50 0 0 0 0 % R
% Ser: 0 8 22 15 15 8 8 36 8 8 8 15 8 50 15 % S
% Thr: 8 0 0 0 8 0 0 0 8 8 8 8 8 8 15 % T
% Val: 0 8 8 0 8 0 15 0 15 36 0 29 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _